Sequence Analysis in Mohali

New Sequencing technologies generate massive amount of biological data. To understand the nature of raw data and produce meaningful information is called Annotation. This annotation can be done with the help of computers by using molecular biology softwares and biological databases. The term “sequence analysis” implies subjecting an amino acid sequence or nucleotide sequence to sequence alignment, sequence databases, repeated sequence searches, or other bioinformatics methods on a computer. Sequence analysis can be used to assign function to genes and proteins by the study of the similarities between the compared sequences. Sequence analysis is an automated, computer-based examination of characteristic fragments, e.g. of a DNA strand.
Key Topics Covered
•    Introduction to Bioinformatics and its applications
•    Molecular Biology of the cell
•    DNA and Amino Acids/ Genes and proteins
•    Biological Databases and their significance (Case study)
•    Biological Sequence analysis and Annotation/ Genome/ Proteome analysis
•    Identification of gene-structures, reading frames, distributions of introns/ exons and regulatory elements
•    Genomics and Proteomics tools and softwares (Case study)
•    Gene and Protein identification
•    The comparison of sequences in order to find similar and dissimilar in compared sequences (sequence alignment)
•    Finding point mutations or the single nucleotide polymorphism (SNP) in organism in order to get the genetic marker
•    Revealing the genetic diversity of organisms
•    Function annotation of genes

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